Conducting Polymer Microcups for Organic Bioelectronics And Drug Delivery
"Development of sensitive and selective biosensors and bioelectronics is of considerable interest for neural interface technologies. The performance of neural interfaces relies on the physical, chemical and electrical properties of the electrode materials, which enable long-lasting communications. Development of sensitive and selective biosensors and bioelectronics is of considerable interest for neural interface technologies. The performance of neural interfaces relies on the physical, chemical and electrical properties of the electrode materials, which enable long-lasting communications.

This templating method uses poly (pyrrole) (PPy), a conducting polymer (CP) for fabrication of monodisperse conducting polymer microcups with tunable surface morphology, electrical properties, controlled drug loading and sustained drug release. Electrical conductivity and in-vitro drug-release profile for the PPy microcups have been characterized in the lab.  "
Applications
  • Bioelectronics
  • Drug delivery
  • Neural interface
  • Axonal regeneration 
Problems Addressed
  • Existing electrodes utilize metallic materials and are not compatible with neural tissue
  • Incorporation of biomolecules using existing methods have shown to hinder electrical properties of CPs
  • Another challenge is creation of monodisperse CP microstructures with tunable surface morphology 
Competitive Advantages
  • Capable of diagnosing impending complications in ESPs 
  • Automatically generates solutions to correct and prevent the complication
  • Can extend the life expectancy of ESPs
  • Increases the production time of ESPs
  • Reduces production loss and replacement costs
Patents
  • Provisional patent application filed
Publications
  • Antensteiner M, et al. (2017). Conducting Polymer Microcups for organic bioelectronics and drug delivery applications. Advanced Materials 29(39). (https://www.youtube.com/watch?v=nAf6tQ4JaUs)
Case ID
2017-066
Inventor
Mohammad Reza Abidian
Associate Professor of Biomedical Engineering
Category